Cytoplasmic ring of the human nuclear pore complex from isolated HeLa nuclear envelopes
Mosalaganti S, Obarska-Kosinska A, Siggel M, Taniguchi R, Turonova B, Zimmerli CE, Buczak K, Schmidt FH, Margiotta E, Mackmull MT, Hagen WJH, Hummer G, Kosinski J, Beck M
Science (2022) 376 pp. eabm9506-eabm9506 [ DOI: doi:10.1126/science.abm9506 Pubmed: 35679397 ]
Structure of nuclear pore complex from HEK cells with GP210 knockout
Mosalaganti S, Obarska-Kosinska A, Siggel M, Taniguchi R, Turonova B, Zimmerli CE, Buczak K, Schmidt FH, Margiotta E, Mackmull MT, Hagen WJH, Hummer G, Kosinski J, Beck M
Science (2022) 376 pp. eabm9506-eabm9506 [ DOI: doi:10.1126/science.abm9506 Pubmed: 35679397 ]
Nuclear pore complex from intact HeLa cells
Mosalaganti S, Obarska-Kosinska A, Siggel M, Taniguchi R, Turonova B, Zimmerli CE, Buczak K, Schmidt FH, Margiotta E, Mackmull MT, Hagen WJH, Hummer G, Kosinski J, Beck M
Science (2022) 376 pp. eabm9506-eabm9506 [ DOI: doi:10.1126/science.abm9506 Pubmed: 35679397 ]
Inner/spoke ring of the human nuclear pore complex from isolated HeLa nuclear envelopes.
Mosalaganti S, Obarska-Kosinska A, Siggel M, Taniguchi R, Turonova B, Zimmerli CE, Buczak K, Schmidt FH, Margiotta E, Mackmull MT, Hagen WJH, Hummer G, Kosinski J, Beck M
Science (2022) 376 pp. eabm9506-eabm9506 [ DOI: doi:10.1126/science.abm9506 Pubmed: 35679397 ]
Nuclear ring of the human nuclear pore complex from isolated HeLa nuclear envelopes
Mosalaganti S, Obarska-Kosinska A, Siggel M, Taniguchi R, Turonova B, Zimmerli CE, Buczak K, Schmidt FH, Margiotta E, Mackmull MT, Hagen WJH, Hummer G, Kosinski J, Beck M
Science (2022) 376 pp. eabm9506-eabm9506 [ DOI: doi:10.1126/science.abm9506 Pubmed: 35679397 ]
Human nuclear pore complex (dilated)
Resolution: 50.0 Å
EM Method: Subtomogram averaging
Fitted PDBs: 7r5j
Q-score: 0.026
Mosalaganti S, Obarska-Kosinska A, Siggel M, Taniguchi R, Turonova B, Zimmerli CE, Buczak K, Schmidt FH, Margiotta E, Mackmull MT, Hagen WJH, Hummer G, Kosinski J, Beck M
Science (2022) 376 pp. eabm9506-eabm9506 [ DOI: doi:10.1126/science.abm9506 Pubmed: 35679397 ]
- Nuclear pore complex protein nup205 (228 kDa, Protein from human)
- Nuclear pore complex protein nup133 (129 kDa, Protein from human)
- Nucleoporin nup37 (36 kDa, Protein from human)
- Nuclear pore complex protein nup107 (106 kDa, Protein from human)
- Nuclear pore complex protein nup155 (155 kDa, Protein from human)
- Nuclear pore glycoprotein p62 (53 kDa, Protein from human)
- Nuclear pore complex protein nup98 (91 kDa, Protein from human)
- Nuclear pore complex protein nup88 (83 kDa, Protein from human)
- Nuclear pore complex protein nup214 (213 kDa, Protein from human)
- Human nuclear pore complex from hek cells (Cellular component from Homo sapiens)
- Nuclear pore membrane glycoprotein 210 (205 kDa, Protein from human)
- Nucleoporin nup35 (34 kDa, Protein from human)
- Nucleoporin seh1 (39 kDa, Protein from human)
- Nucleoporin p54 (55 kDa, Protein from human)
- Aladin (59 kDa, Protein from human)
- Nuclear pore complex protein nup96 (106 kDa, Protein from human)
- Nucleoporin p58/p45 (60 kDa, Protein from human)
- Protein sec13 homolog (35 kDa, Protein from human)
- Nucleoporin nup188 homolog (196 kDa, Protein from human)
- Nuclear pore complex protein nup93 (93 kDa, Protein from human)
- Nuclear pore complex protein nup85 (75 kDa, Protein from human)
- Protein elys (252 kDa, Protein from human)
- Nuclear pore complex protein nup160 (162 kDa, Protein from human)
- E3 sumo-protein ligase ranbp2 (358 kDa, Protein from human)
- Nucleoporin nup43 (42 kDa, Protein from human)
- Nucleoporin ndc1 (76 kDa, Protein from human)
Human nuclear pore complex (constricted)
Resolution: 12.0 Å
EM Method: Subtomogram averaging
Fitted PDBs: 7r5k
Q-score: 0.034
Mosalaganti S, Obarska-Kosinska A, Siggel M, Taniguchi R, Turonova B, Zimmerli CE, Buczak K, Schmidt FH, Margiotta E, Mackmull MT, Hagen WJH, Hummer G, Kosinski J, Beck M
Science (2022) 376 pp. eabm9506-eabm9506 [ DOI: doi:10.1126/science.abm9506 Pubmed: 35679397 ]
- Nuclear pore complex protein nup205 (228 kDa, Protein from human)
- Nuclear pore complex protein nup133 (129 kDa, Protein from human)
- Nuclear pore complex (120 MDa, Cellular component from Homo sapiens)
- Nucleoporin nup37 (36 kDa, Protein from human)
- Nuclear pore complex protein nup107 (106 kDa, Protein from human)
- Nuclear pore complex protein nup155 (155 kDa, Protein from human)
- Nuclear pore glycoprotein p62 (53 kDa, Protein from human)
- Nuclear pore complex protein nup98 (91 kDa, Protein from human)
- Nuclear pore complex protein nup88 (83 kDa, Protein from human)
- Nuclear pore complex protein nup214 (213 kDa, Protein from human)
- Nuclear pore membrane glycoprotein 210 (205 kDa, Protein from human)
- Nucleoporin nup35 (34 kDa, Protein from human)
- Nucleoporin seh1 (39 kDa, Protein from human)
- Nucleoporin p54 (55 kDa, Protein from human)
- Aladin (59 kDa, Protein from human)
- Nuclear pore complex protein nup96 (106 kDa, Protein from human)
- Nucleoporin p58/p45 (60 kDa, Protein from human)
- Protein sec13 homolog (35 kDa, Protein from human)
- Nucleoporin nup188 homolog (196 kDa, Protein from human)
- Nuclear pore complex protein nup93 (93 kDa, Protein from human)
- Nuclear pore complex protein nup85 (75 kDa, Protein from human)
- Protein elys (252 kDa, Protein from human)
- Nuclear pore complex protein nup160 (162 kDa, Protein from human)
- E3 sumo-protein ligase ranbp2 (358 kDa, Protein from human)
- Nucleoporin nup43 (42 kDa, Protein from human)
- Nucleoporin ndc1 (76 kDa, Protein from human)
cryoEM structure of human Nup155 (residues 19-981)
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7r1y
Q-score: 0.48
Mosalaganti S, Obarska-Kosinska A, Siggel M, Taniguchi R, Turonova B, Zimmerli CE, Buczak K, Schmidt FH, Margiotta E, Mackmull MT, Hagen WJH, Hummer G, Kosinski J, Beck M
Science (2022) 376 pp. eabm9506-eabm9506 [ DOI: doi:10.1126/science.abm9506 Pubmed: 35679397 ]
- Nup155 from homo sapiens (Cellular component from Homo sapiens)
- Nuclear pore complex protein nup155 (154 kDa, Protein from Homo sapiens)
Human nuclear pore complex in HIV-1 infected T cells
Zila V, Margiotta E, Turonova B, Muller TG, Zimmerli CE, Mattei S, Allegretti M, Borner K, Rada J, Muller B, Lusic M, Krausslich HG, Beck M
Cell (2021) 184 pp. 1032-1046.e18 [ DOI: doi:10.1016/j.cell.2021.01.025 Pubmed: 33571428 ]
Allegretti M, Zimmerli CE, Rantos V, Wilfling F, Ronchi P, Fung HKH, Lee CW, Hagen W, Turonova B, Karius K, Bormel M, Zhang X, Muller CW, Schwab Y, Mahamid J, Pfander B, Kosinski J, Beck M
Nature (2020) 586 pp. 796-800 [ DOI: doi:10.1038/s41586-020-2670-5 Pubmed: 32879490 ]